From oils, pills, chocolates, creams, and even gummy bears, CBD products are all the rage these days.  You can find CBD products online or in your local drug store or supermarket, promising relief from a wide range of human and animal health conditions such as seizures, anxiety, heart disease, and other disorders.

However, one common concern among people who use CBD for chronic illnesses is whether it will interfere with psychedelic medicine.

CBD and psychedelic medicines, such as psilocybin-producing mushrooms, are becoming more widely available, but it's important to understand how they interact together.

While the two substances have some similarities, using either one is a unique experience.


What is CBD? 

Cannabidiol (CBD) is from the Cannabis Sativa plant (hemp). It is a substance found in products such as oil and edibles that helps to calm and relax people. It alleviates anxiety by altering the brain's receptor response to serotonin.

CBD is commonly used in medicine for pain management. There have also been reports of CBD being used to treat back pain, osteoarthritis, and cancer.


Psychedelic Medicines

Psychedelic medicine is a drug that affects the serotonin receptors in the brain, causing a variety of changes in vision, hearing, and thought and an altered state of consciousness. LSD (acid), psilocybin (magic mushrooms), MDMA (ecstasy), and DMT (dimethyltryptamine) are all examples of psychedelic drugs with different pharmacological profiles.

Medical research institutions worldwide conducted extensive research on the use of psychedelic substances to treat illnesses such as depression, anxiety, addiction, and posttraumatic stress disorder (PTSD). Preliminary findings concluded that psychedelic medication-assisted treatments yielded positive results, with significant clinical improvements and few side effects.

Psychedelic substance research was halted from the 1950s to the early 1970s, resulting in it being classified as a "drug of abuse" with no recognized medical value. According to a study, the general public is often unaware of the medicinal value of psychedelic medicines. The public is only aware of their potential harm when patients use illicit substances without a prescription. 


Research on Combining CBD and Psychedelic Medicines

Cannabidiol and psychedelic medicines have piqued the interest of research organizations wanting to treat combination disorders. The University of Miami Miller School of Medicine has received funding to investigate the efficacy of combining CBD and the psychedelic drug psilocybin in treating and preventing symptoms of traumatic brain injury and posttraumatic stress disorder. According to one study, 40% of people who have had a Traumatic Brain Injury (TBI) experience a change in mental status or consciousness, referred to as PTSD.

CBD has been used to treat the symptoms of traumatic brain injury, such as hearing loss, balance issues, memory issues, and cognitive issues. Psilocybin, which is found in magic mushrooms, on the other hand, has been used to treat brain-related conditions, and its properties may have an impact on the treatment of PTSD. Other medications can mask the individual symptoms of these conditions, but using Cannabidiol and psychedelic medicine increases the likelihood that they will treat the combined disorder.


Benefits of Combining CBD and Psilocybin (magic mushrooms) in Psychedelic Medicine

CBD and psilocybin are safe and natural, with few to no side effects, making them better than over-the-counter medications. Combining the two enables you to enjoy enhanced effects.

  1. Improves your moods

CBD and psilocybin have similar effects on mood and depression. Mushrooms are adaptogenic, which means they can improve your mood and reduce the effects of stress on your body. On the other hand, CBD's anxiolytic and antidepressant effects allow it to combat symptoms such as mood swings. When combined, CBD and psilocybin will help you revert to positive thinking whenever you have negative thoughts.

  1. Reduces your anxiety

 CBD and psilocybin are both effective antidepressants. CBD oil is used to treat depression and anxiety without causing some adverse side effects. The combination of CBD and psilocybin is effective in inducing abstract thinking, which reduces anxiety.

  1. Helps you focus

Anecdotally, some people say that psilocybin helps them manage chronic anxiety, depression, and attention deficit hyperactivity disorder symptoms when taken in small doses, called microdosing. A study published in the journal Psychopharmacology used the results of an international survey conducted in 2018 about the effects of microdosing. According to the survey, of 1,102 participants, 44% said microdosing significantly improved their mental health, with 50% successfully discontinuing antidepressants and nearly 40% discontinuing psychiatric medications. 19% of the respondents said microdosing resulted in “no perceived changes” in their mental health, and only 1.3% reported that microdosing made their mental health “somewhat worse.”

On the other hand, CBD users claim that it gives them a sense of calm because it interacts with receptors to lower their heart rate, allowing them to focus more effectively. Combining the two can maintain the high concentration required at work or in daily activities.

  1. Improves your mental health

Dopamine is in charge of thoughts that we interpret as good feelings. The dopamine-induced thought direction is reinforced by combining CBD and psilocybin. A combination of the two substances ensures that you have control over the outcomes of your thoughts.

  1. Improves your appetite

CBD can provide relief for people who are suffering from eating disorders like bulimia and anorexia. The compound has shown the potential of activating the appetite of people who are stressed.

When mushrooms are combined with CBD, the psilocybin cancels out the harmful effects of Cannabidiol. Similarly, CBD cancels out the adverse effects of psilocybin.

  1. Boosts your immunity

CBD has anti-inflammatory properties and can help relieve pain in cancer patients. Cannabidiol is also a powerful antioxidant.

Like CBD, mushrooms also have antioxidant properties. According to some studies, mushrooms may be beneficial in the fight against cancer as they shield cells from DNA damage and halt tumour growth. Mushrooms are also high in fibre, protein, and vitamin B.

Because CBD relieves cancer patients' symptoms and pain, combining it with mushrooms will enhance the effects on users.



As the world continues to improve, medical researchers have delved deeper into discovering new ways to treat ailments, alleviate physical and mental pain, and find a cure for new diseases. While some prescribed drugs are effective, there is still fear and uncertainty among the public, who frequently question its downside and how it may even worsen the patient's condition.

People with certain medical conditions who are being treated with psychedelics have tried consuming Cannabidiol, which has reduced psychotomimetic effects. Although the potential impact of combining the two substances is still unknown, the practice is already familiar to people suffering from certain diseases. Current research, however, indicates that the two can interact synergistically, assisting a person in recovering from various symptoms of certain illnesses. However, it should be noted that improper use of these substances can lead to addiction and further complicate one's health. Patients must follow the correct dosage at all times.

Medical institutions and research organizations will conduct more research and treatments involving Cannabidiol and psychedelic medicine in the coming years. If researchers can one day determine all of the possible effects of combining these two substances, it will be a game-changer in the medical field and will help save more lives.