Cannabigerol (CBG) is a type of cannabinoid that is acquired from the cannabis plant. It can be found in most cannabis strains and is known as one of the non-psychoactive cannabinoids. Like Tetrahydrocannabinol(THC), CBG responds with the brain's cannabinoid receptors, but unlike THC, CBG helps alleviate paranoia caused by the former.
CBG is obtained through specific Cannabis strains bred to express higher amounts of CBG and also from younger cannabis plants which contain higher concentrations of Cannabigerol than the mature plants.
The body's endocannabinoid system processes the Cannabidiol (CBD). The endocannabinoid system consists of an extensive network of cellular receptors throughout a human's brain and body. The brain's "cannabinoid" receptors surpass most receptor types; they are in charge of most of the levels and activities of the neurotransmitters. The "cannabinoid" receptors adjust to whatever the system needs, whether alertness, hunger or temperature. In the stimulation of these receptors, our body produces endocannabinoid molecules that are similar to the molecular structure of the cannabis plant.
Every human has tiny cannabis-like molecules that are found floating in our brains. The first endocannabinoid found is named anandamide after the Sanskrit word "ananda," which means bliss.
BENEFITS OF CBG
Similar to CBD, CBG is mainly utilized to relieve pain. Multiple pieces of research have shown that CBG can be used as an effective treatment for numerous symptoms and conditions. It has been observed to have antimicrobial, antibacterial, anti-inflammatory and anticancer benefits without the intoxicating effects of THC.
Studies on CBG look very promising, but more research and peer-reviewed studies are needed to uncover this compound's true potential.
CBG has appetite-stimulating effects, as found in a 2015 study on rats. Compared to the control group, the rats administered CBD was able to eat twice the amount of food served. Appetite stimulation is important in the medical field, especially with chemo-induced appetite loss and appetite issues in people living with HIV.
A study titled "Uncovering the Hidden Antibiotic Potential of Cannabis (2020)" determined that CBG has strong antibacterial properties. CBG is effective against methicillin-resistant staphylococcus aureus (MSRA) strains that cause drug-resistant staphylococcus infections that are not easily treatable.
Researchers from a 2015 study investigated a number of non-psychotropic phytocannabinoids, like CBD, CBG, cannabidivarin (CBDV), Δ9-tetrahydrocannabivarin (THCV) and cannabichromene (CBC) on mouse bladder contractility. They discovered that CBG is the most effective at treating dysfunctional bladders, followed by THCV, CBD, and CBDV.
According to one research, CBG is proven to hamper colon cancer progression as it impedes the growth of colorectal cells (CRC), which, when left unattended, causes multiple cancers in the digestive and excretory systems. CBG also blocks TRPM8 channels that promote cancer growth.
With the anti-inflammatory properties of CBG, it helps reduce harmful eye pressure caused by glaucoma. One study concluded that it also assists in the production of aqueous humour outflow, a fluid that helps with the nourishment of the eye.
EHP-102, a compound found in cannabigerol, is proven to show numerous benefits on the nervous system and has noticeable effects on reducing inflammation and decreasing neuronal loss in Parkinson's and Huntington's Disease in mice.
INFLAMMATORY BOWEL DISEASE
Inflammatory Bowel Disease is an incurable disease that millions of people suffer from. Personal and scientific evidence suggests that CBG may prove beneficial for IBD patients. In one study, colitis was introduced to mice through intracolonic administration of dinitrobenzene sulphonic acid (DNBS). CBG was then also administered to the mice, and it significantly reduced the effects of DNBS on colon weight and colon length ratio. These results imply that CBG can provide special protection with proper doses.
CBG is mainly consumed as an oil but is relatively pricier and rarer than other cannabinoids. The most common CBG products are CBG flowers, CBG gummies, CBG isolate, CBG tincture, CBG chewing gum, CBG sublingual tablets, CBG salve, and CBG softgels. CBG is used as a supplement with other cannabinoids to increase its efficacy, and this process is called the entourage effect.
HOW LONG DOES CBG STAY IN A PERSON’S SYSTEM
CBG stays in our system depending on varying factors. These include:
- Your Dosage is self-explanatory; the higher the CBG you consume, the longer it will stay in your system. The lower the dose, the easier it is to metabolize and disappear in your system.
- Frequency of Consumption - Taking CBG consistently means it will accumulate in your system and stay there for longer. If you take it occasionally, it will make it stay in your system for a shorter amount of time.
- Your Metabolism - Every person has a unique metabolism, which means CBG will be circulated and metabolized at varying rates for different people. It usually stays in the system for 24-48 hours, but if you’re taking it for higher doses, it has a high chance of staying in your system for up to a week.
A study on US citizens 21 and up who had used CBD for the past six months last September 2021 reported that although CBG has helped them with anxiety, chronic pain, depression, insomnia, and paranoia, it also came with dry mouth, sleepiness, hunger and dry eyes as side-effects. Most respondents disclosed that CBG is more effective in treating different conditions than regular medicine, but it still carries a risk of multiple side effects and also addiction.
WHAT KIND OF FUTURE AWAITS CBG?
CBD and THC are the most common alternative treatment methods, but CBG is at the forefront of major breakthroughs in different fields, especially in healthcare, because of its numerous benefits and huge potential. With this potential also comes massive amounts of research to be undertaken. It is only a matter of time before we see CBG products as household items.